Pharmacology 3620 Lecture Notes - Lecture 10: Drug Metabolism, Angina Pectoris, Superior Vena Cava
24 Oct 2016
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Feel free to email me (oneclass512475@gmail. com) if you have any questions or don"t understand something! To describe what happens after a drug is administered orally. To describe why some drugs must be administered with food and others must be taken on an empty stomach. Describe the advantages and disadvantages of various routes of drug administration. To identify the impact of blood flow and solubility on drug absorption. To identify factors that influence drug absorption in each of the routes of administration. Enteral: oral and rectal anything given within the intestinal tract. Parenteral: intravenous (iv), intramuscular (im), subcutaneous (subq) This is the most common route as it is cheap and convenient. Oral administration also allows time for intervention during the phase when the drug is still being absorbed into the tract. Disadvantages: incomplete/variable absorption (first pass effect), interaction with food, impractical for unconscious patients. Food can delay the absorption of some drugs, impacting pharmacokinetics of the drug: e. g.
