Physiology 2130 Lecture Notes - Lecture 12: Carbonic Acid, Peripheral Chemoreceptors, Metabolic Acidosis

• School: Western University
• Department: Physiology
• Course: Physiology 2130
• Professor: Anita Woods

Document Summary

Regulation of hydrogen ion concentration: buffers body fluids bind free h+ not remove and stabilizes ph. [immediate: respiratory system regulate h+ conc. from volatile acids [within seconds/minutes, kidneys strong control over h+ conc. particularly non-volatile acids [hours or days] Respiratory system regulation of h+ conc: one of the functions of respiratory system is removal of co2 which keeps the ph relatively constant, co2 is detected by the central and peripheral chemoreceptors. Increase in co2 levels cause increase in ventilation thus more co2 removed. Hco3- and h: the hco3- leaves by simple diffusion into circulation and. Acidosis can occur when too little hco3- or too much h+ Alkalosis can occur when too much hco3- or too little h+ Both these can occur in 2 forms respiratory and metabolic. Respiratory acidosis caused by decreased ventilation and increased pco2: anything that causes decreased ability to remove co2, brain damage or lung damage, counteracted by buffers in blood and excretion of excess.