Physiology 2130 Lecture Notes - Lecture 10: Baroreceptor, Central Chemoreceptors, Carotid Sinus

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Air contains roughly 21% o2, resulting in a po2 of 159 mmhg. Once in the lungs where the po2 in 105 mmhg, o2 quickly diffuses down its partial pressure gradient into the blood where the po2, wich was initially at 40 mmhg, rises to roughly 100 mmhg with the fresh o2. Here, where the po2 is high, o2 will bind to hemoglobin, forming oxyhemoglobin. As the blood flows through the tissue, where. Po2 is low (cause these places need oxygen), o2 will dissociate from hemoglobin and diffuse into the cells, down its partial pressure gradient. Then co2 comes in through these 3 ways Origin of respiration: originates from medulla oblongata, contains two areas: Inspiratory center: activates inspiratory muscles: active process requiring diaphragm & intercostals. Pneumotaxic centers: gas regulation, pons ensure proper amounts of o2 and co2 by modifying signals in medulla, pneumotaxic center: regulates rate of breathing, apneustic center: controls depth of inhalation and exhalation, requires negative feedback, set point.

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