Physiology 2130 Lecture Notes - Lecture 2: Buffy Coat, Fluid Compartments, Cell Membrane

• School: Western University
• Department: Physiology
• Course: Physiology 2130
• Professor: Christine Bell

Document Summary

Homeostasis- the maintenance of relatively stable conditions in our internal environment. Body is divided into intracellular fluid compartment(icf) and extracellular fluid compartment (ecf) Ecf is further divided into interstitial fluid compartment (fluid bathing cells) and plasma (watery portion of blood) Icf makes up 22% of total body water. Ecf (interstitial) makes up 26. 4% of total body water. Plasma (ecf) makes up 6. 6% of total body water. Pale, yellow fluid consisting of 92% water and 8% other substances (e. g. proteins, ions, nutrients, gases, and waste) A colloidal solution (liquid containing suspended substances that do not settle out of solution) Suspended substances are plasma proteins: albumins, globulins, fibrinogen. Water intake through digestive tract matches water loss from kidneys, lungs, digestive tract and skin. There is small ion difference between plasma and interstitial fluid (both ecf) Bigger ecf: sodium ions (na+), calcium ions (0 in icf, ca2+), chloride ions (cl-) Bigger icf: potassium ions (k+), protein ions (pr)