Physiology 3120 Lecture Notes - Lecture 2: Penicillin, Proteoglycan, Microvillus

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So blood enters corpuscle and substances taken out of the blood goes into corpuscle to make up the filtrate. Arranged in series so blood enters corpuscle via afferent arteriole, goes through capillary bed with corpuscle and out efferent arteriole. Nephron structure more twisted than flattened structure of nephron seen before. So have afferent arteriole going into corpuscle, proximal tubule, descending limb, loop of henle and ascending limb that flips over to go behind corpuscle to become distal convoluted tubule. Junction between ascending limb and distal convoluted tubule passes in between afferent and efferent arteriole. Glomerulus is the capillary bed located at corpuscle. Nephrons have two capillary beds: glomerulus at corpuscle and peritubular/vasa recta at tubules. Capillary bed in corpuscle allows filtration of substances that are taken out of blood. Capillary bed around tubule allows reabsorption of substances that were previously taken out from blood but need to go back into body.

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