Rehabilitation Sciences 3060A/B Lecture Notes - Lecture 11: Autoantibody, Ankylosis, Fibrocartilage

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Understand the role of altered mechanics in contributing to the deformity. Ra involves exacerbations and remissions that progressively damage joints. Disease begins insidiously (for no apparent reason), often beginning with small joints like those in the fingers. As ra progresses, joint involvement is usually symmetrical and of several joints upper cervical spine and temporomandibular joint are also involved. The severity of the condition varies from mild to severe, reflecting the number of joints affected, degree of inflammation, and how fast the disease progresses. Systemic = can affect other systems of the body. Causes chronic inflammation of connective tissue mainly seen in joints. Ligaments and tendons potential source of pain. Ligaments hold bones together and prevent undesirable motion stabilizes joint. Tendons control joint motion and convey low level muscle tone for joint stability. Type a cells ingest and remove bacteria and debris by phagocytosis. Type b cells constantly secreting hyaluronate (binding agent giving synovial fluid its viscous quality)

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