BI110 Lecture : BI 110-Oct 18.docx
Document Summary
Homework: aplia assignment due oct 28, midterm marks up today, lab assignment due thursday at 10:30am. Why it matters: the two are interrelated. Mutations in cftr gene (encodes chloride pump) cause cystic fibrosis (cf) Cells and organelles need barrier to separate internal and external contents. Membrane proteins: integral proteins (usually transmembrane), peripheral membrane proteins (attached to surface, not embedded) Fluid mosaic model of cell membrane: fig 5. 1, pg 93. All proteins synthesized on er, which travel through many structures to get to plasma membrane in order for carb group to be added to protein. Fluid mosaic model supported by experimental evidence-membranes are fluid (fig. Cells isolated from 2 diff species (human and mouse cell) Membrane proteins of human cell: red dye; of mice cell: green. After fusion, half of cell is green and half is red. 40 mins later membrane proteins were mixed all over cell, because proteins would be able to migrate over cell.
