BI226 Lecture Notes - Lecture 25: Cystic Fibrosis, Neurofibromatosis, Mendelian Inheritance

11 views4 pages
30 Dec 2019
School
Department
Course

Document Summary

Large family pedigree used to locate the huntington disease (hd) gene. Mapping of huntington disease : detection of linkage between the dna marker g8 and the. Hd locus: segregation of the g8 dna marker (four alleles - a, b, c, and d) in a large. The lod score is a statistical tool for studying linkage: used to determine if data are sufficient to conclude with confidence that a disease gene and a marker are linked. Lod = log prob. (observed results if loci are linked at a given rf) Cystic fibrosis (cf) symptoms were first described in 1938, but the genetic cause of the disorder was not known, and there was no effective treatment for the 1/2000 caucasian north. In 1989, geneticists were able to pinpoint a precise locus for the cf gene by looking directly at. The discovery was a collaborative effort led by drs.

Get access

Grade+
$40 USD/m
Billed monthly
Grade+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
10 Verified Answers
Class+
$30 USD/m
Billed monthly
Class+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
7 Verified Answers

Related Documents

Related Questions