BIOL 1000 Lecture 3: Learning Objectives-Gene Expression and Continuity
21 Feb 2019
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Gene expression; genetic continuity and variation reproduction, chromosomes, recombination and meiosis. Define key terms (dna replication): semiconservative replication: a new polynucleotide chain is assembled on each original chain as 2 chains unwind. Template and complementary copy chains remain wound together when replication is complete producing a dna molecule wih one old and one new strand. Dna polymerase: enzymes that assemble complementary nucleotide chains from individual nucleotides. nucleotide triphosphates (datp, dgtp, dctp, dttp): substrated for polymerization reaction catalyzed by dna polymerases. Composed of: nitrogenous base linked to a deoxyribose sugar linked to a 3 phosphate group chain. atp is the same just with a ribose sugar. Dna helicase: enzyme that catalyzes the unwinding which exposes both strands for the next steps in replication. Uses energy from atp hydrolysis to unwind dna helix. Replication fork: y-shaped structure produced by unwinding of dna that consists of 2 unwound template strands transitioning to double helical dna.
