BIOL 1000 Lecture Notes - Lecture 8: Motor Protein, Microfilament, Microtubule

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Eukaryotic cells: distinct nucleus surrounded by nuclear envelope, membrane bound organelles0 endomembrane system. Divide cell into functional & structural compartments called organelles. Organelles: membrane bound, found in eukaryotic, specialized function, suspended in cytosol. Hypothesis: through evolution, many membranes derived from same one. Physically separates our hereditary material from the rest of the cells. Double membrane (phospholipid bilayer) connected to the er. Chaperon proteins that help import things out/into nucleus. Structure made up of proteins & nucleic acid. Ribosomal rna is transcribed & assembled in nucleolus. Made of filaments of proteins called laminnes. Dna & associated proteins (histones & non-histone proteins) It changes based on the needs of the cell. Nucleosome: in eukaryotic chromosomes, consisting of dna coiled around histones. Histone octamer (2 each of histones h2a, h2b, h3, h4) which dna wraps around. Octamer b/c there"s 2 set of 4 histones. Binding of histone h1 causes nucleosomes to package into a coiled structure (solenoid or 30nm chromatin fibre).

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