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Lecture 3

Lecture 3 - Genetics.docx

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Department
Biology
Course
BIOL 1000
Professor
Michael Gadsden
Semester
Fall

Description
BIOL 1010 Lecture 3 07/10/2010 Notes from last week  More than one virus type to affect certain hosts  The proteins are different, when mixed a new virus pops out of it o This is dangerous because our bodies don’t have antibodies to fight it (eg. H1N1 or H1N3 etc.)  Exchange of genetic material to create a brand new virus E coli and Molecular Biology  Watch ANIMATIONS ON THE BOTTOM  Viruses o Is it alive? Unknown because of the fact that they can only manipulate host cells o In the nucleus (where the viral DNA is kept) is where new viruses are made  Retroviruses o Special class of +RNA using Reverse Transcriptase to make new viruses grow o RNA-DNA-RNA  dsRNA o once injected into the host cell it enters the nucleus, reproduces and then codes for DNA to RNA to make proteins  Viral Envelope  phospholipid membrane o Derived from host and has viral proteins in it o Naked inject DNA into cell o Like bacteriophages o GENOME (inner); Viral Capsid (hexagon), Envelope (Circle) o Ie. Lambda virus – see sheet 4  Membrane Fusion o Envelope of the virus becomes part of the host cell membrane o Capsid opens and releases genomes into the cell o When exiting the cell it binds to the membrane and uses this as an envelope of the virus  rRNA (continued) o has a job to do (tertiary structure) and therefore has a phenotype  Conservative o How many genotypes and phenotypes remain the same as evolution occurs  Natural Selection o The environment selects (via certain selective pressures
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