BIOL 2020 Lecture Notes - Lecture 15: Ascending Limb Of Loop Of Henle, Afferent Arterioles, Efferent Arteriole

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Movmenet of water between icf and ecf: occurs due to a change in ecf osmolarity. Ecf osmolarity, you will notice higher osmolarity inside the cell, and it will suck up some water and the cell will swell. If you re-arrange the equation, you can see that volume of compartment = number of particles in the ecf /icf osmolality. The loop of henle the business end of which is the thick ascending limb of the loop of henle. In the distal tubule, we have reabsorption into the peritubular capilalries, and in the collecting duct we have reabsorption and excretion : na+ reabsorption, the regulation of renal tubular sodium reabsorption is a critical issue. Na is mainly reabsorbed in proximal tubule (for the bulk) and fine-tuning happens in the collecting duct. In the proximal tubule, the major regulators are sympathetic ns and angiotensin ii. Activation of both of those systems augments the reabsorption of sodium from the proximal tubule.

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