BIOL 2020 Lecture Notes - Lecture 20: Reduction Potential, Cytochrome C Oxidase, Q Cycle

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29 Apr 2016
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Review: etc creates a proton gradient that powers atp production. Glycolysis takes place in cytoplasm (outside of mitochondria) Pyruvate is transported into the matrix where it is converted to acetyl-coa. High concentration of protons corresponds to ph (lower ph outside than inside) therefore there is a spontaneous diffusion though the membrane. Key players: complex i, complex ii, ubiquinone (uq, complex iii, cytochrome c, complex iv, each carrier in the chain has a higher af nity for electrons (or standard reduction potential) than the previous carriers. Electrons can be transferred from nadh or fadh2 through these players because each new player has a higher af nity than the last. Most components of the electron transport chain (etc) are located in four complexes. Function as oxidoreductase enzymes: because ultimate point is to reduce oxygen, this is the general name for these enzymes. Complex i (nadh dehydrogenase complex) catalyzes transfer of electrons from nadh to ubiquinone (uq or simply q )

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