BIOL 2021 Lecture Notes - Lecture 2: Lipid Bilayer, Red Blood Cell, Glycerophospholipid
28 Jan 2017
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1-25: eukaryotic cell- interesting stuff happens around membranes (nuclear, plasma, golgi apparatus, 10- 1a: tem red blood cell- thin slice thru red blood cell- plasma membrane. 10-1b: lipid bilayer (double) + proteins (protrudes out of membrane)- membrane in living cells, non covalently attached, 50/50 weight for proteins to lipid. Fatty molecules, amphiphilic (hydrophobic and hydrophilic interactions) Consist of: polar- hydrophilic head (choline, phosphate and glycerol, non- polar- hydrophobic tail (fatty acid tail, one tail is saturated, other tail is unsaturated- has one or more cis- double bonds (kink, phosphoglycerides. Phosphate head group (hydrophilic part- choline, serine, and anolamine) 10-3: four major phospholipids in mammalian plasma membrane *recognize structures* 3 phosphoglycerides (different head groups): ptd etn (phosphotidylethanolamine, ptd ser (phosphotidylserine- negative charge, ptd cho (phosphotidylcholine, sphingolipids. Sphingomyelin: sphingosine backbone (instead of glycerol like in phosphoglycerides, phosphate, amino group (nh3) and 2 hydroxyl groups (oh, choline head group attached to terminal hydroxyl.
