BIOL 2021 Lecture Notes - Lecture 2: Sterol, Glycosylphosphatidylinositol, Cardiolipin
12 May 2013
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Document Summary
Barrier to water soluble molecules: this is because of the non-polar interior bilayer. Separate inside from outside: cell vs. environment, organelle vs. cytosol. Maintain ion gradient: energy conversion (i. e. mitochondria for atp production, signalling. Signalling: plasma membrane receptors, relay of signals from inside the cell. Transmembrane proteins go across lipid bilayer ~5nm: 50:50 lipid to protein by weight (it is noted that by function, this can change exponentially) Lipids: fatty molecules, amphiphillic two natures hydrophillic at one end and hydrophobic at the other, main categories of membrane lipids in animal cells: Phosphoglyderide is a glycerol backbone and two fatty acids [usually one unsaturated and one saturated] + head group. 4 major phospholipids in the mammalian plasma membrane (pm: phosphoglycerides (look these up, be able to recognize them) Sphingomyelin = sphingosine + fatty acid + choline head group. Animal glycolipids sphingosine + fatty acid + sugars. Bacterial and plant glycolipids glycerol backbone + 2 fatty acids + sugars.
