KINE 1020 Lecture 3: KINE 1020-Week 2- Lecture 3 and 4

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Muscle weakness- failure to develop an expected force which can be attributed any one of the processes required for force generation. This is associated with all types and examples of muscle diseases/ disorders. Acetylcholine diffuses across the neuromuscular junction, stimulating acetylcholine receptors depolarize the muscle membrane: the result is the contraction of the muscle fibre. Contraction depends on the integrity of each of these parts; disease or disorder in any part causes muscle weakness. Classification: upper motor neuron disease- a problem from cerebral cortex down to the spinal cord y cv- stroke producing weakness of one side of the body. Muscular dystrophies- are a group of hereditary disorders (n=9) characterized by progressive muscular atrophy and weakness. In most varieties the muscles of the limb girdles- the pelvic and should muscles- are involved. Progressive loss of muscle size, and strength which is caused by loss of muscle proteins laer changing to muscle fibre death and tissue death.

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