KINE 3670 Lecture 10: Lecture 10
24 Dec 2015
School
Department
Course
Professor
Document Summary
Ionotropic ligand binds, conformation change, pore opens, quick transfer, ap starts quickly. Metabotropic no pore, slow response, second-messenger system (like cyclic. Need to know some things, we"ll discuss in detail later on. Dopamine is related to drugs and addiction the reward system. Ach to seratonin will be discussed histamine won"t be covered. We will focus on nitric oxide when we talk about learning and memory. Little discussion in endocannabinoids and marijuana we have andogenous ligands and receptors for it. Unconventional not stored in vesicles like the remaining neurotransmitters. Most of the neurotransmitters are excitatory gaba and glycine are the two inhibitory ones. One of the major nt in muscles. Decline of memory in alzheimer"s patients they are given pills that can improve memory (they are ache inhibitors) Ache only nt that is digested into it"s halves; becomes choline and acetate. Choline is taken back via the uptake transporter in exchange for sodium and is recycled.
