KINE 4010 Lecture Notes - Lecture 6: Cytochrome, Phosphocreatine, Cytochrome C Oxidase
30 Sep 2016
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Document Summary
For every 2 protons coming back in you make 1 atp molecule as long as there is adpf available. Adpf is the limiting factor for this reaction. Phosphate is always in plentiful supply where do the 2 h protons come from. From the build up of h ion gradient or proton gradient those protons got there because electrons flowed from protein complexes( sometimes referred to as cytochromes) in three locations. That electron"s movement along the cytochomres is coupled with protons pumping into im, ultimately making a gradient, which come flowing back through providing kinetic energy ti be transferred to chemical energy and we make atp. First from the nadh2 ( output of kreb"s cycle) here e split the atom and electron is pumped in complexes. So cyanide kills you because of that blockage. Nadh is oxidized h is pumped to outside while electrons flowing between complexes.
