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Cancer.docx

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Department
Kinesiology & Health Science
Course
KINE 1020
Professor
Angelo Belcastro
Semester
Winter

Description
Cancer • Cancer unregulated or abnormal cell growth • Over 200 kinds  Cancer Cycle 1. Genetic mutation at the DNA level a. Carcinogens b. Ageing c. Infections d. Radiation e. Inherited 2. Abnormal cell proliferation (multiplication) a. Unregulated multiplication of cells possessing genetic mutation 3. Tumor formation a. Benign b. Pre­cancerous c. Malignant  d. Angiogenesis – increased blood supply 4. Metastasis  a. Spread to other tissues and organs via bloodstream/lymphatic system b. New tumors may form Cancer Related Genes DNA Repair Genes: Drivers Ed • Fix mutations within the cell before they have a chance to be passed on via cell division Tumor Suppressor Genes: Brakes • Stop cell growth and control cell death (apoptosis) • 50% of cancers are believed to be related to missing/damaged tumor sup. Genes Oncogenes: Gas Pedal • Mutations of proto­oncogenes • Accelerate cell growth and encourage cell proliferation Stages of Cancer • Stage is based on the size of the tumor, whether it is invasive or not, whether lymph nodes are involved  and whether the cancer has spread • Increased b
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