NATS 1670 Lecture 5: Winter Lecture 5 - Diversity of Viruses – Replication and Growth
7 Feb 2017
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Document Summary
Viruses are highly diverse in overall morphology and in the nature of their genetic material: different method of replication, different structure and size, host range. Virus needs to replicate in order to stay in the environment. Cannot survive on its own, replicating using host enzyme etc. Viral genes are incorporated into the host"s chromosome and are transmitted to the host"s daughter cells. Virus genes become part of cell"s genome through development of memory: genome = 1. 5% of genes can make proteins, virus = 8% of genes can make proteins cells. Steps: viral genome enters host cell, viral genome integrates into host-cell genome, host-cell dna polymerase copies chromosome, cell divides. In most cases hiv is a part of the lysogenic cycle. Viral particles are made and released from cell. Steps: viral genome enters host cell, viral genome is replicated and transcribed, viral mrna are translated and proteins processed, particles assemble inside host, particles exit to exterior.
