NATS 1670 Lecture Notes - Lecture 2: Smallpox Vaccine, Swine Influenza, Cutter Laboratories

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Vaccination and passive immunization: diseases became very less after the introduction of vaccines. Diseases such as measles, polio, rubella, diphtheria, mumps and pertussis: proportion of deaths due to infectious diseases. 1880 63: life expectancy went up high post-vaccines. Vaccines are victims of their own success. Most parents today have never seen a case of diphtheria, measles, or other once-common disease now preventable by vaccines. As a result, some parents wonder why their children must receive shots for diseases that don"t seem to exit. Vaccines safety issues: allergies to egg and gelatin, opv reversion to wild type, swine flu vaccine and gbs, smallpox vaccine. Vaccine tragedy: ipv- the cutter incident. 40000 cases of polio leaving 200 children with different degrees of paralysis killing 10. Measles (worldwide: one of the leading causes of death among young children, 2001: >40 000 000 infections and 1000 000 death, 2004: approx. 20 000 000 infections and 240 000 death: controlled strongly by vaccination.

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