NATS 1670 Lecture Notes - Chemokine Receptor, Tenofovir Disoproxil, Envelope Glycoprotein Gp120

• School: York University
• Department: Natural Science
• Course: NATS 1670
• Professor: Motti Anafi

Document Summary

Residual replication of hiv , even on haart. If people stop taking the virus will comeback, it never leaves the body. Truvada prevents hiv infection: a drug that treats people who arent hiv positive but they have a chance to be exposed to this virus. The first pill to prevent hiv, not a treatment a prevention. Hiv- entry into the cell: enters like other virus, it need a receptor o o o o. Helper t(cd4+) cells are major target for hiv. However such a binding by itself isnt enough for the virus to enter the cell chemokine receptor ccr5 is necessary co-receptors along with cd4. Receptor mutations and hiv infection: 25% of long term hiv survivors (carriers for long time without full aids) have a specific ccr5 mutation In the middle ages there was a plant that killed a third of europe"s population.