SOCI 3630 Lecture Notes - Lecture 47: Multiple Endocrine Neoplasia, Diabetes Mellitus Type 1, Polycystic Ovary Syndrome
4 Jun 2020
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Hyperglycemia: caused by cumulative effects from the following: Increased glucagon secretion due to islet cells. T2: at dx, then q1yr if no ckd. T1: 5 yr post dx, and then q1yr. To further lower the risk of nephropathy and retinopathy. History of recurrent severe lvl of functional dependecy hypoglycemia. Longstanding diabetes cannot reach goals despite effective doses of multiple hypoglycemics. A 1c b lood pressure c holesterol d rugs for vascular protection. An a1c value less than or equal to 7 % should be targeted. Should aim for a blood glucose target of 4 7 mmol/l. Should aim for a blood glucose target of 5 10 mmol/l. A1c target less than or equal to 7 % cannot be achieved with a post-meal target of 5 10 mmol/l, further post-meal lowering to. Get to target within 3-6 months of diagnosis (a1c lowering) Increases insulin sensitivity in the liver and peripheral tissues. Dosing and go slow to minimize gi ae"s.
