BIOSCI 106 Lecture Notes - Lecture 8: Amphiphile, Acetyl-Coa, Saturated Fat
6 Sep 2013
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Document Summary
Consists of triglycerides, phospholipids and cholesterol esters. All are poorly soluble in water and therefore difficult to digest and absorb. Bile salts are secreted from the gall bladder to help emulsify the lipids. Lipids must be packaged to be absorbed by epithelial cells from the intestinal lumen. The parcel that transport the lipids in the digestive tract are called micelles, this occurs when several bile salts surround a lipid droplet. Lipoproteins are used to transport lipids in the blood stream. Depends on bile salts, they have hydrophobic and hydrophilic sides, amphipathic, are able to interact with nonpolar lipid and aqueous environment. Lipases bind the micelle and degrade it into monoacylglycerols and fatty acids, this occurs in the gut lumen. Fatty acids bind to albumin in the blood. The fatty acids are further metabolised in epithelial cells with binding proteins and atp, this forms a triglyceride. This is reacted with a phospholipid to form chylomicrons (this occur in endoplasmic reticulum)
