BIOL 3210 Lecture Notes - Lecture 21: Succinic Acid, Citric Acid, Sulfur
Document Summary
Chymotrypsin is the only enzyme where the mechanism needs to be memorized, you can put it on your card for the test though. The hub of metabolism is the citric acid cycle the final catabolic pathway for amino acids, carbs, and fatty acids. The acetyl group is oxidized, the carbos are released as co2 and the electrons go to nad and fad. A single nucleotide produced (gtp), but in some cells its atp. Chemical logic of each reaction is written on the figure on the slide. Suggests to cut and order the reactions: atp is not the key purpose, it"s just a bonus, the electron carriers! Remember thioesters are high in energy: cleaving bond drives the reaction, homodimer and the active site is made by the two pieces. There is substrate ordering they have to bind in a certain order. **compare and contrast the last two steps on the slide to steps 6 and 7 of glycolysis.
