NUSCTX 103 Lecture Notes - Lecture 5: Dietary Fiber, Psyllium, Glycosidic Bond
3 Dec 2020
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Document Summary
Cellulose: major component of dietary fiber, abundance carbohydrate structural material that is present in plant cell walls, undergoes packing that is strengthened by intermolecular hydrogen bonds, b1,4 linked glucose polymer that is not digested by human saccharides. Insoluble vs soluble: fiber supplements, metamucil, active ingredient in psyllium seed husks, used to treat constipation and improve intestinal movement, mostly considered to be soluble fiber, absorb water. Increase fecal bulk: side effects gas and cramping might occur. Interfere with micelle formation: decrease access to digestive enzymes, reduced intestinal mixing of food, very high amounts of dietary fiber can interfere with mineral bioavailability, positive aspects of reduced/slowed intestinal absorption: Improved glucose tolerance: lowered serum cholesterol levels, 1. Fibers may bind bile acids/impair micelle formation fiber in large quantities impairs micelle formation because fiber binds to bile and can remove it from enterohepatic circulation: 2. Interference with mixing and accessibility of lipids, proteins, starches to digestive enzymes for breakdown: 3.
