BIOL 118 Lecture Notes - Lecture 15: Cellular Respiration, Conformational Change, Oxidative Phosphorylation

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Mitochondria = power generating station (figure 7. 14: two membranes. Next steps occur in mitochondria: pruvate moves into the mitochondria, pyruvate processing (2) and the citric acid cycle (3) occur in the mitochondrial matrix. Pyruvate processing: occurs in the mitochondrial matrix, enzyme is pyruvate dehydrogenase, requires coenzyme a. Pyruvate reacts with coenzyme a (coa) to produce acetyl coa. One of pyruvate"s carbons oxidized to co2. Two remaining carbons are transferred to coa. The citric acid cycle (krebs cycle: eight small carboxylic acids (r-cooh) These molecules are not used up in cell respiration: acetyl coa is oxidized to co2, figure 9. 10. Citrate (the first molecule in the cycle) Formed from acetyl coa and oxaloacetate (the last molecule in the cycle) The two remaining carbons from pyruvate are oxidized to co2: results. 1 atp( or gtp) (but remember glucose yields 2 pyruvates so for a glucose, this is doubled!)

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