CH-2230 Lecture Notes - Lecture 19: Cyclohexane Conformation, Substituent
2 Apr 2016
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Slide 53: biggest group on the front opposite the biggest group on the back (most stable) Slide 55: chair cyclohexane (look straight down on the molecule) the hydrogens on each carbon alternate between straight up and straight down (axial). The other hydrogens are equatorial. (one hydrogen is axial and one is equatorial on each carbon) if the ring is lipped, the axial hydrogen becomes an equatorial hydrogen and vice versa conformaion of. Slide 57: monosubsituted cyclohexanes: 1-2 diaxial interacion, when the subsituent is in the axial posiion it"s not as stable because of the hydrogen posiions. Slide 58: disubsituted cyclohexanes cis-1,4-dimethylcyclohexane (cis = same side, methyl is on the same side) vs. trans-1,4-dimethylcyclohexane (trans = opposite side) Slide 61: c is most stable, d is least stable. Slide 62: trans-1-tert-butyl-3-methylcyclohexane (will always be axial up, equatorial down, on the 1 carbon in the top right corner) second structure on the slide is more stable b/c the bigger group is equatorial.
