GEN-3000 Lecture Notes - Lecture 2: Microtubule, Telophase, Cytoplasm
Document Summary
Mitosis is all about splitting up genetic material. Before a cell can divide, it must first duplicate the chromosomes stored in its nucleus. Dna replication takes place: prophase - chromosomes start to condense. Can now distinguish one chromosome from the next. Chromosome from mom has no impact on chromosome from dad: prometaphase - nuclear envelope completely disintegrated. Spindle fibers connect to kinetochores: metaphase - chromosomes all lining up in middle at metaphase plate. These chromosomes are the most condensed they will be in this phase: anaphase - sister chromatids move towards opposite poles. Now the chromosomes each have their own centromere so there are more. You count the centromeres to know how many chromosomes you have: telophase - chromosomes on opposite poles. Some textbooks book count this as a part of telophase. Spindle fibers essential to movement and the function of the cell and chromosomes!!!! If you stop the spindle fiber from working, it will stop the cell from dividing.
