FGSS 2140 Lecture Notes - Lecture 8: Female Sperm Storage, Pituitary Gland, Ejaculation

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Lecture #8: regulation of the testis (review) (see handout/image in book, lh and testosterone. 1. testosterone is the messenger: hypothalamus (gnrh) acting on pituitary, acting on ley- dig cells which release androgen testosterone. 2. negative feedback by (protein hormone) inhibin (that can act on hypothalamus or the pi- tuitary) Modulators of testis function (prolactin, gnrh, oxytocin, osteocalcin) 1. oxytocin (from leydig cells) & gnrh (from sertoli cells) made in testes. 4. difficult to figure out what hormone affect spermatogenesis. Fsh for first stage of mitosis and all stages of mitosis and meiosis testosterone works with fsh for first mitosis, first meiotic division, and spermiogenesis. Fsh synergizes: increases androgen receptors on sertoli cells (in spermiogenesis: system for storage and delivery of gametes, testes. 1. some sperm are store in the seminiferous tubules and the tete testis. Ii. epididymus: most sperm storage, maturation: gain the ability to fertilize.

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