HLTH 220 Lecture Notes - Lecture 14: Reduced Form, Anaerobic Glycolysis, Catabolism

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6 Dec 2016

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Metabolism: the sum of all the chemical reactions that take place within the 10 trillion cells in the body. These reactions follow metabolic pathways: the end-product of one chemical reaction is the starting product for the next reaction. Anabolic reactions - require atp to combine smaller molecules, such as glucose. Micronutrients from foods are metabolized to release energy for atp synthesis. Macronutrients are disassembled into co2 and h20 while capturing the released energy as adenosine triphosphate (anabolism) Macronutrients are oxidized in this metabolic pathway. Oxidation/oxidized: chemical process of giving up electrons. Coenzymes accept and transport the electrons removed from macronutrients. Synthesis requires niacin and tryptophan or aspartic acid. Atp is a high-energy molecule composed of adenine, ribose, and three phosphate molecules. Any source of macronutrients can be used to generate atp. Breaking of the phosphate bond releases energy than can be used to metabolic reactions.

Related Questions

7. In metabolism, food gets oxidized and the coenzymes NAD⁺ and FAD are reduced.

	True
	False

8. Which of the following does not undergo oxidation or reduction during metabolism?

	A. lipids
	B. Coenzyme A
	C. carbohydrates
	D. FAD

9. Which of the following is not a coenzyme?

	A. NAD⁺
	B. Coenzyme A
	C. ATP
	D. FAD

10. Which of the following is false regarding FAD?

	A. FAD is an oxidizing agent.
	B. FAD is the oxidized form.
	C. FAD is a coenzyme
	D. FADH₂ is an oxidizing agent.

11. How many carbon atoms are present in an acetyl group?

	A. 1
	B. 2
	C. 3
	D. 4

12. The purpose of coenzyme A is to deliver acetyl groups to the citric acid cycle.

	True
	False

13. What reacts with NADH and FADH₂ to form NAD⁺ and FAD?

	A. carbon dioxide
	B. water
	C. ATP
	D. oxygen (and H⁺)

14. Which metabolic process oxidizes NADH and FADH₂

	A. electron transport chain
	B. oxidative phosphorylation
	C. citric acid cycle
	D. hydrolysis

15. Which metabolic process converts ADP to ATP?

	A. electron transport chain
	B. oxidative phosphorylation
	C. citric acid cycle
	D. hydrolysis

......Use the following to feel out the sentense: cycled, photosynthesis, cellular respiration, oxygen, carbon dioxide, ATP

During ____________ , mitochondria break down carbohydrates to produce energy that is used to make ____________ .

This process requires ____________ and carbohydrates, and produces ____________ and water.

During ____________ , chloroplasts use water and ____________ to create carbohydrates.

This process requires ____________ and water, which are byproducts from ____________ .

In turn, it produces ____________ and carbohydrates that are used in ____________ .

In this manner, the flow of energy is ____________ between chloroplasts and mitochondria.

..........use the following to feel out each sentense: from, oxidized, photosynthesis, cellular respiration, gains, to, loses, reduced.

During ____________ , hydrogen atoms are transferred ____________ water ____________ carbon dioxide as glucose forms.

Thus, during ____________ , carbon dioxide is ____________ , while water is ____________ . In other words, carbon dioxide ____________ electrons and water ____________ electrons.

During ____________ , glucose is ____________ as oxygen is ____________ , becoming water.

In each of these reactions, while one molecule loses electrons (is ____________ ), another gains electrons (is ____________ ); thus, each of these metabolic pathways includes redox reactions: coupled reduction and oxidation reactions.

..........use the following to feel out the sentenses: increase, conservation of energy, first of thermodynamics, input, decrease, laws of thermodynamics, secod law of thermodynamics, heat

The ____________ explain energy flow and energy conservation and can be applied to biological systems.

The ____________ states that energy cannot be created or destroyed, also known as the law of ____________ .

The ____________ states that energy is lost when it is converted from one form to another, often in the form of ____________ .

As cells go through transformations, they ____________ the total entropy of the universe, resulting in a ____________ in available energy.

For example, photosynthesis in plants requires an energy ____________ to turn carbon dioxide and water into sugar because there is a ____________ in entropy.

1. C6H12O6 + 6O2 Ã 6CO2 + 6H2O Glucose is being _____ to _____ and oxygen is being _____ to _____. a. oxidized; carbon dioxide; reduced; water b. oxidized; water; reduced; carbon dioxide Incorrect c. reduced; water; oxidized; carbon dioxide d. reduced; carbon dioxide; oxidized; water

2. Which of the following stages in the breakdown of the piece of toast you had for breakfast generates the most ATP? a. the citric acid cycle Incorrect b. glycolysis c. the digestion of starch to glucose d. oxidative phosphorylation

3. Which of the following is a catabolic pathway? a. gluconeogenesis b. production of starch Incorrect c. glycolysis d. production of glycogen

4. Per molecule, the oxidation of a fatty acid results in _____ energy storage than the oxidation of glucose. a. the same b. less Incorrect c. more d. None of the above; fatty acids cannot be oxidized.

5. Of the eight reactions in the citric acid cycle, how many are oxidation-reduction reactions? a. one b. two c. three d. four e. five

6. The process of glycolysis transfers the energy in sugar molecules into the stored energy of activated carriers such as ATP and NADH. Which statement is true about glycolysis? a. Only eukaryotic organisms do glycolysis. b. The ten reactions of glycolysis are identical in all eukaryotic cells, but are different in prokaryotic cells due to their diverse metabolic strategies. Incorrect c. The ten reactions of glycolysis are identical in almost all living organisms on the planet. d. There are many ways to oxidize glucose and transfer energy into activated carriers; the diversity of organisms on the planet is reflected in the diversity of their mechanisms of glycolysis.

7. Referring to the sentence completed in #13 above, the purpose of the latter reaction (in active muscle cells) is to _____. a. accumulate lactic acid in the cell, which provides additional energy for the production of ATP Incorrect b. slow down glycolysis until oxygen becomes available again c. accelerate the Krebs cycle, which will restore the oxygen supply d. regenerate NAD+ so that glycolysis can continue in the absence of oxygen

8. What are the products of the citric acid cycle? a. carbon dioxide, NADH, FADH2 and GTP b. carbon dioxide, NAD+, FAD and GTP c. NADH, FADH2, and acetyl CoA Incorrect d. carbon dioxide and water

9. Which statement is true about enzymes? a. Enzymes catalyze chemical reactions because they make inherently endergonic reactions exergonic. b. Each enzyme in a cell can catalyze many different chemical reactions involving chemically different substrates. Incorrect c. Enzymes can only catalyze reactions in one direction. d. After catalyzing a reaction, an enzyme is permanently altered and can no longer bind substrate. e. None of the above is true. 1

10. âG measures the change in free energy in a system as it converts reactant (Y) into product (X). When [X] = [Y], âG is equal to _____. a. RT b. ÎGÂ° + RT c. ÎGÂ° d. ln [X]/[Y]

11. The âGÂ° for the hydrolysis of ATP is -7.3 kcal/mol. What conditions in the cell would lead to a âG for ATP hydrolysis of -11 kcal/mol? a. An increase in the ATP/ADP ratio b. An increase in anabolic activity in the cell c. Transport of ATP out of the compartment where the reaction is occurring Incorrect d. A decrease in the ATP/ADP ratio

12. In the first reaction of glycolysis, a phosphate transferred from ATP to a glucose molecule to produce glucose-6-phosphate and ADP. Under conditions existing in the cell, the free energy change for this reaction is -8.0 kcal/mole. Which of the following statements is true? Recall that the âGÂ° for the hydrolysis of ATP is -7.3 kcal/mol. a. Glucose concentrations in the cell are always low, making this reaction more favorable than would be expected. b. This reaction is less favorable than would be expected, given the âGÂ° of ATP hydrolysis. c. Glucose-6-P concentrations in the cell are very low relative to glucose concentrations, making the reaction more favorable than would be expected. d. The âGÂ° for the addition of a phosphate to glucose must be -0.7 kcal/mole.

13. Protein E can bind to two different proteins, S and I. The binding reactions are described by the following equations and values: E + S --> ES Keq for ES = 10 E + I> EI Keq for EI = 2 Given the equilibrium constant values, which one of the following statements is true? a. When S is present in excess, no I molecules will bind to E. b. E binds I more tightly than S. c. The binding energy of the ES interaction is greater than that of the EI interaction. d. Changing an amino acid on the binding surface of I from a basic amino acid to an acidic one will probably make the free energy of association with E more negative.

HLTH 220 Lecture Notes - Lecture 14: Reduced Form, Anaerobic Glycolysis, Catabolism

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