BSC 1086C Lecture Notes - Lecture 13: Mitochondrial Matrix, Acetyl-Coa, Citric Acid Cycle

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30 Mar 2017

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10-step pathway: anaerobic, occurs in the cytosol, glucose -> 2 pyruvic acid molecules. Final products of glycolysis: 2 pyruvic acid. Converted to lactic if o2 not readily available. Enter aerobic pathways if o2 is readily available: 2 nadh + h+ (reduced nad+, net gain of 2 atp. Breakdown products of fats and proteins can also enter the cycle. Cycle intermediates may be used as building materials for anabolic reactions. The part of metabolism that directly uses oxygen. Chain of proteins bound to metal atoms (cofactors) on inner mitochondrial membrane. Substrates nadh + h+ and fadh2 deliver hydrogen atoms. Transfer of energy from nadh + h+ and fadh2 to oxygen releases large amounts of energy. This energy is released in a stepwise manner through the electron transport chain. Glycogenesis: glycogen formation when glucose supplies exceed need for atp synthesis, mostly in liver and skeletal muscle. Glycogenolysis: glycogen breakdown in response to low blood glucose.

Related Questions

QUESTION 1

Which of the following is the correct order of the three stages of cellular respiration?

	a.	Krebs cycle, glycolysis, electron transport
	b.	electron transport, glycolysis, Krebs cycle
	c.	Krebs cycle, electron transport, glycolysis
	d.	glycolysis, Krebs cycle, electron transport
	e.	electron transport, Krebs cycle, glycolysis

1 points

QUESTION 2

Consider a bacterial cell that performs anaerobic respiration. If that bacterial cell had access to six molecules of glucose to use, how many ATP molecules would it be able to produce?

	a.	2
	b.	34
	c.	36
	d.	6
	e.	12

1 points

QUESTION 3

The oxygen that organisms need to live is used exclusively in which of the following metabolic pathways?

	a.	Electron transport chain
	b.	Anaerobic respiration
	c.	Glycolysis
	d.	Krebs cycle
	e.	ATP-Synthase

1 points

QUESTION 4

The electron transport chain uses the energy in NADH and FADH₂ to pump H⁺ ions from the matrix to the innermembrane space. The H⁺ gradient is then used to power ATP-Synthase. Enough H⁺ is pumped from the energy in a molecule of NADH to produce ______ ATP molecules, while enough H⁺ is pumped from the energy in a FADH₂ molecule to produce ______ ATP molecules.

	a.	three; two
	b.	three; three
	c.	two; two
	d.	two; three

1 points

QUESTION 5

Which of the following list contains only products of cellular respiration?

	a.	glucose, oxygen, ADP
	b.	ATP, carbon dioxide
	c.	oxygen, ADP, carbon dioxide
	d.	ATP, glucose, oxygen
	e.	glucose, ATP

1 points

QUESTION 6

What powers the enzyme ATP-Synthase?

	a.	NADH molecules
	b.	oxygen (O₂)
	c.	ATP
	d.	NADH and FADH₂ molecules
	e.	The H⁺ gradient between the matrix and inner-membrane space

1 points

QUESTION 7

Organisms exist which are able to survive using only glycolysis (i.e. without using oxidative phosphorylation).

True

False

1 points

QUESTION 8

Each ADP molecule contains ________ phosphates, and each ATP molecule contains ________ phosphates.

	a.	three; three
	b.	two; two
	c.	one; two
	d.	two; three
	e.	one; three

1 points

QUESTION 9

Adding a phosphate group to ADP to form ATP is an endergonic reaction.

True

False

1 points

QUESTION 10

The majority of ATP produced during cellular respiration is produced during glycolysis.

True

False

1 points

QUESTION 11

Glycolysis occurs:

	a.	on enzymes located in the inner-membrane.
	b.	in the cytosol.
	c.	in the inner-membrane space.
	d.	in the nucleus of the cell.
	e.	in the matrix of mitochondria.

1 points

QUESTION 12

Muscle soreness associated with strenuous exercise is due to:

	a.	the production of alcohol during anaerobic respiration.
	b.	a buildup of lactic acid.
	c.	an excessive amount of ATP that builds up during exercise.
	d.	the large amounts of CO₂ building up in the muscle.

1 points

QUESTION 13

A required reactant for glycolysis is:

	a.	the electron transport chain.
	b.	carbon dioxide.
	c.	oxygen.
	d.	NAD+.
	e.	mitochondria.

1 points

QUESTION 14

NADH is produced in all of the following except:

	a.	the electron transport chain.
	b.	the Krebs cycle.
	c.	glycolysis.

Question 1 Organisms exist which are able to survive using only glycolysis (i.e. without using oxidative phosphorylation).
True
False

Question 2 Glycolysis occurs:
a. in the matrix of mitochondria.
b. in the inner-membrane space.
c. in the cytosol.
d. in the nucleus of the cell.
e. on enzymes located in the inner-membrane.

Question 3 Muscle soreness associated with strenuous exercise is due to:
a. the large amounts of CO2 building up in the muscle.
b. an excessive amount of ATP that builds up during exercise.
c. a buildup of lactic acid.
d. the production of alcohol during anaerobic respiration.

Question 4 Each ADP molecule contains ________ phosphates, and each ATP molecule contains ________ phosphates.
a. two; three
b. two; two
c. three; three
d. one; three
e. one; two

Question 5 The oxygen that organisms need to live is used exclusively in which of the following metabolic pathways?
a. Glycolysis
b. Electron transport chain
c. Krebs cycle
d. Anaerobic respiration
e. ATP-Synthase

Question 6 NADH is produced in all of the following except:
a. the electron transport chain.
b. glycolysis.
c. the Krebs cycle.

Question 7 Consider a bacterial cell that performs anaerobic respiration. If that bacterial cell had access to six molecules of glucose to use, how many ATP molecules would it be able to produce?
a. 36
b. 6
c. 12
d. 34
e. 2

Question 8 The majority of ATP produced during cellular respiration is produced during glycolysis.
True
False

Question 9 What powers the enzyme ATP-Synthase?
a. The H+ gradient between the matrix and inner-membrane space
b. ATP
c. oxygen (O2)
d. NADH molecules
e. NADH and FADH2 molecules

Question 10 Which of the following list contains only products of cellular respiration?
a. ATP, glucose, oxygen
b. ATP, carbon dioxide
c. oxygen, ADP, carbon dioxide
d. glucose, ATP
e. glucose, oxygen, ADP

Question 11 Adding a phosphate group to ADP to form ATP is an endergonic reaction. True False

Question 12 The electron transport chain uses the energy in NADH and FADH2 to pump H+ ions from the matrix to the innermembrane space. The H+ gradient is then used to power ATP-Synthase. Enough H+ is pumped from the energy in a molecule of NADH to produce ______ ATP molecules, while enough H+ is pumped from the energy in a FADH2 molecule to produce ______ ATP molecules.
a. two; three
b. three; three
c. three; two
d. two; two

Question 13 Which of the following is the correct order of the three stages of cellular respiration?
a. glycolysis, Krebs cycle, electron transport
b. Krebs cycle, electron transport, glycolysis
c. electron transport, Krebs cycle, glycolysis
d. electron transport, glycolysis, Krebs cycle
e. Krebs cycle, glycolysis, electron transport

Question 14 A required reactant for glycolysis is:
a. carbon dioxide.
b. mitochondria.
c. NAD+.
d. the electron transport chain.
e. oxygen.

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Question 1

Which of the following statements regarding photosynthesis and cellular respiration is true?

	A.	Photosynthesis occurs in mitochondria, and cellular respiration occurs in chloroplasts.
	B.	Photosynthesis occurs in chloroplasts, and cellular respiration occurs in mitochondria.
	C.	Photosynthesis occurs in mitochondria and in chloroplasts.

Question 2

How do cells capture the energy released by cellular respiration?

	A.	They produce glucose
	B.	The energy is coupled to oxygen
	C.	They produce ATP

Question 3

During redox reactions

	A.	the loss of electrons from one molecule is called reduction
	B.	electrons are lost from one substance and added to another substance
	C.	protons from one molecule replace the electrons lost from another molecule

Question 4

Oxidation is the ________, and reduction is the ________.

	A.	gain of oxygen; loss of oxygen
	B.	loss of electrons; gain of electrons
	C.	gain of protons; loss of protons

Question 5

During cellular respiration, NADH

	A.	delivers its electron load to the first electron carrier molecule.
	B.	is chemically converted into ATP
	C.	is the final electron acceptor

Question 6

A drug is tested in the laboratory and is found to create holes in both mitochondrial membranes. Scientists suspect that the drug will be harmful to human cells because it will inhibit

	A.	the citric acid cycle only.
	B.	glycolysis only
	C.	the citric acid cycle and oxidative phosphorylation

Question 7

Which of the following metabolic pathways is common in aerobic and anaerobic metabolism?

	A.	glycolysis
	B.	the citric acid cycle
	C.	electron transport chain

Question 8

Which of the following is a result of glycolysis?

	A.	production of CO2
	B.	a net loss of two ATPs per glucose molecule
	C.	conversion of glucose to two three-carbon compounds

BSC 1086C Lecture Notes - Lecture 13: Mitochondrial Matrix, Acetyl-Coa, Citric Acid Cycle

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