EHS 385 Lecture Notes - Lecture 6: Atp Synthase, Phosphorylation, Citic Group
Document Summary
Relies on oxygen to produce atp following breakdown for energy. Can yield much more energy (atp) than anaerobic systems. Primary method of energy production during endurance events. Formation of pyruvate from glycolysis: occurs in cytosol, if oxygen present, steps 2-3 occur. Citric acid cycle (krebs cycle: pyruvic acid (3 carbon) converted to acetyl-coa (2 carbon) [co2 given off] Acetyl -coa combines with oxaloacetate (4 carbon) to form citrate (6 carbon) Citrate metabolized to oxaloacetate ( 2 co2 given off) Produces 3 molecules of nadh and 1 fadh2. To complete the oxidation of carbohydrates, fats, and proteins by forming nadh and fadh. Often involves transfer of hydrogen atoms rather than free electrons: hydrogen atom contains on electron, molecule that loses both hydrogen and an electron, molecule oxidized. Transport hydrogens and associated electrons: to mitochondria for atp generation (aerobic, to convert pyruvic acid to lactic acid (anaerobic) nicotinamide adenine dinucleotide (nad)