11:067:330 Lecture 14: Vitamins + Minerals (Cpt 9 + 10)

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Vitamins organic compounds required in small amounts. Fat-soluble (a, d, e, k) or water-soluble (c, all b) Nutrients, but not metabolic fuels (glucose, fas) or structural nutrients (aas, calcium) **act as facilitators of metabolism of other nutrients. Fat-soluble vitamins must be consumed in diet. Vitamin c can be synthesized by most mammals, but primates must get vitamin c from diet. B vitamins cannot be synthesized by mammals but are synthesized by microbes during fermentation. Pro-vitamins compounds that are chemically changed by body into vitamins. B-carotene converted to vitamin a by body. Aa tryptophan converted by microbes to niacin. In both cases, pro-vitamin must be consumed in order to be available for conversion. Closely tied to metabolism: highly productive animals require more vitamins. 4 b vitamins involved in conversion of pyruvate to acetyl coa. Pantothenic acid part of coa molecule. Thiamin required for synthesis of thiamin pyrophosphate (component of pdh)

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