01:146:295 Lecture Notes - Lecture 13: Dementia With Lewy Bodies, Frontotemporal Dementia, Cerebrospinal Fluid

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When comparing the brain structure of someone suffering for alzheimer"s to a normal individual the brain has a noticeably reduced volume mainly in the cerebral cortex because of nerve cell death. One consequence of cell dead is the expansion of the ventricles. The ventricle contains cerebral spinal fluid (csf) and when the other cells dies off the csf spreads out filling up the spaces. The hippocampus is located within the temporal lobe, it is one of the first areas of the brain affected. It appears that earlier memories are not stored in the hippocampus which is why long- term memories aren"t affected until more progressive stages of the disease. Old memories are stored throughout the cerebral cortex. Dementia is a big term covering many symptoms that affect memory and thinking to the point in which it affects a person"s ability to perform daily activities. Alzheimer"s accounts for 80% of dementia related illnesses. Other forms of dementia include lewy body dementia,

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