BIO 103 Lecture Notes - Lecture 10: Genetic Engineering, Gene Gun, Dna Ligase
24 Oct 2017
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Direct manip of org"s genes by tech intervention/manip. Phrase used to describe modern techniques in molecular bio (i. e. recombinant dna) Tech used to alter genetic materials of living cells and or in orddr to make them capable of producing new substances/perofrm new functions. 60s discovery of restriction enzymes, dna ligase. 70s dev of first recombinant dna molecule. First expression of foreign gene in bacteria. Production of insulin via g. e. (in bacteria) Field testing of ge plants resistant to insects, viruses, and bacteria, transgenic sheep tracy" (human gene for alpha-1-antitrypsin expressed in her milk) Transgenic beltsville pig (gene for human growth-hormone) 90s first gene therapy trial in humans and first publicly reported patient death. Genetically altered tomatoes sold in us supermarkets. 2000s - completion of first draft of human genome. First human embryo cloned, first cloned cat, human genome completed. Gene therapy experimental technique that uses genes to treat or prevent disease.
