PSYC 405 Lecture Notes - Lecture 12: Apolipoprotein E, Donepezil, Cholinesterase
13 Mar 2020
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Document Summary
Apoe-4 is present in about 20% of the population. Also subtle, but measurable negative effects on cognition in healthy normal adults (mielke et al. , 2014). healthy adults aged 60 and over, with no signs of ad yet . Appear protected from effects of high amyloid deposits if. They engage in highly cognitively stimulating activities in middle adulthood (jagust & mormino, 2011) Those who inherit apoe-e4 have increased risk for developing. If you inherit two apoe-e4 genes you have an even higher risk. However, presence of these genes is not a guarantee you will develop. Brief memory lapses, forgetting roads, location of keys, No treatment will slow or stop deterioration of brain cells in ad. U. s. food and drug administration approved about five drugs. Temporarily slow down the worsening of symptoms for six to twelve months (on average) Only for approximately half the people who take the drug. Prevent breakdown of acetylcholine, needed for learning and memory.
