BSC 431 Lecture Notes - Lecture 13: Cytoskeleton, Endosome, Motor Neuron

• School: University of Alabama
• Department: Biological Sciences
• Course: BSC 431
• Professor: Julie Olson

Document Summary

Clostridium (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) Can be normal flora in the gut: found in 5% of healthy adults. Some can tolerate low levels of o2. Species of medical importance: perfringens- wound infections that lead to gas gangrene, uterine infections, food poisoning (cid:1, difficile- antibiotic associated diarrhea, pseudomembranous colitis (cid:1) (cid:1) (cid:1) (cid:1) (cid:1, tetani- tetanus, botulinum- foodborne botliusm, infant botulism, wounds, inhalation, perfringens. Cellulitis w/ gas formation: bacteria growing on dead tissue, gas = rapid metabolism of bacteria. Rapid destruction of muscle tissue and systemic spread with high mortality: clostridial myonecrosis (gas gangrene, can lead to loss of a limb or death (cid:1, food poisoning- common. Abdominal cramps, lots of diarrhea but no fever, nausea, or vomiting. Meat products contaminated w/ large numbers of organisms and their enterotoxin: refrigeration prevents growth, reheating easily destroys this toxin.