BSC 444 Lecture Notes - Lecture 10: Plasmodesma, Phloem, Immunodeficiency
5 Oct 2017
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Innate immunity in vertebrates: adaptive immunity in vertebrates, rna silencing, programmed cell death. Rna in cell is degraded: stimulate production of major histocompatibility complex (mhc) class i molecules and proteasome proteins (these molecules enhance the presentation of viral peptides on the infected cell surface to t cells, activation of nk cells. Influenza a virus ns1 protein and hepatitis c virus ns3-4a protein block pathways involved in interferon production: polio virus prevents the synthesis of interferons as a result of general inhibition of cell gene expression. Inducing apoptosis: viral countermeasures against nk cells, reduce nk cell activities, hiv particles in blood alter expression of certain molecules on the surface of. Nk cells -> reduces efficiency of nk cell activities, including the ability to kill virus infected cells. Immunoglobulins = type of glycoprotein (sugars on proteins provide stability: made of 2 heavy and 2 light chains, contain 2 antigen binding sites and a fc region (fragment crystallizable, classes important for antiviral immunity:
