KNES 466 Lecture Notes - Lecture 8: Western Electric, Vasodilation, Longitudinal Study
Document Summary
Established primary risk factors: cigarette smoking. Established by exposing lab animals to substances in cigarette smoke. Causes damage to lining of coronary arteries: dyslipidemia. Over significant amount of time, a certain amount of damage was noted. Greater the dose, greater the response: hypertension, sedentary lifestyle, a primary risk factor--there"s been established through a multitude of studies that there is a cause and effect relationship. Secondary risk factors: have been shown to have a relationship with cad, not cause and effect though, diabetes, obesity, male gender, increased age, high-fat diet, menopause, family history, psychosocial distress, abnormal blood clotting, genetic and hormonal issues. Inflammatory status can be measured by numerous markers, such as: Modifiable v. non-modifiable risk factors: smoking is an example of a modifiable risk factor=it can be changed, dyslipidemia, htn, sedentary lifestyle, all modifiable, male gender, increased age, family history all non-modifiable. Disease incidents: study also showed low ldl, and high hdl was optimal for decrease in.