PSIO 303A Lecture Notes - Lecture 4: Carbohydrate Metabolism, Pancreatic Islets, Impaired Glucose Tolerance

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Distinguish the specific contributions of organs in whole-body glucose homeostasis. Summarize the long term consequences of impairments of whole-body glucoregulation in. Metabolic syndrome and how can oxidative stress contribute to their development. Glucose tolerance in normal individuals and in individuals with metabolic syndrome: In the glucose test --> an individual with normal glucose tolerance can dispose of glucose in two hours. Primary organ systems and their roles in whole-body glucoregulation: This tissue never gives glucose away in its entirety. Major tissue responsible for peripheral disposal of glucose in response to an oral glucose load/meal during endurance exercise. The transport of glucose into muscles is a highly regulated process that is stimulated by hormones (e. g. insulin) or contractions. Molecules of glucose that are transported can be stored as glycogen and oxidized to produce atp. Note: it is not one or the other. It stores it as glycogen and then produces atp.

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