NUR 416 Lecture Notes - Lecture 13: Diabetes Mellitus Type 1, Polyphagia, Diabetes Mellitus Type 2
6 May 2020
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Type 1: absolute insulin deficiency, autoimmune. Immune mediated destruction of beta cells: idiopathic, age of onset <20 yrs, abrupt onset, typically underweight at presentation, tx. Insulin: dka common, usually no family hx. But increased risk if relative with type 1 dm. Probably related to autoimmune diseases because those are genetic: 25% of new cases present in dka, peak of age onset. Early to mid puberty: clinical manifestations. Type 2: decreased pancreatic insulin production & insulin resistance, genetic component & risk factors, older age of onset. Though increasingly occurring in younger children: gradual onset, typically overweight at presentation, tx. Insulin in 20-30: dka uncommon, more likely to have family hx, peak age of onset. Disorder of the pancreas that develops during childhood. Caused by an autoimmune condition that causes destruction of the pancreatic beta cells. Exocrine function: enzymes, not related to this disease. Endocrine function: hormones, islets of langerhans.
