BCS 110 Lecture Notes - Lecture 8: Radial Glial Cell, Visual Cortex, Neuroglia
29 Oct 2018
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Document Summary
Metencephalon- cerebellum is getting bigger so it gets bigger. As cells are generated, they begin moving to their addresses . Migrating cells - immature looking for destination. Tangential : most cells don"t because it takes a lot of effort. Glia-mediated migration: new glial cells climb the radial glial cells- easier way. Radial glial cells are the neuron stem cells. Cells must align with others and form structures. Cell-adhesion molecules (cams) : cell moves along and happens to cross another cell that has a right protein, then they will stick to another (desomasomes) Aggregation of cell junction: in cns- nuclei, in pns - ganglia. Growth cone: extends and retracts filopodia as it finding its way. Growth cone (our arm) and filopodia (our fingers) Two types of cues: short range cues and long range cues. Long-range cues: attract by chemoattraction and repulse by chemorepulsion. Short -range cues: contact repulsion and contact attraction. Fasciculation: first axon that does all the hard work.
