Question 1 10 pts
What three kinds of cells are infected by HIV?
macrophages, T-Helper cells and dendritic cells
B-cells, skin cells and T-helper cells
B-cells, T-Helper cells and T-killer cells
macrophages, dendritic cells and cytotoxic T-cells
Question 2 10 pts
Sometimes an HIV infected cell is not killed immediately after infection, but lives on, and continues to be a source of the infection for the lifetime of the patient. What is the mechanism that allows the HIV virus to remain in the cell, to get passed down to all descendants of that cell, and to retain the ability to be reactivated for the lifetime of the patient?
Question 3 10 pts
List the three processes that viruses are dependent on their host cells for.
1.
2.
3.
Question 4 10 pts
What does the ELISA test for HIV infection measure?
HIV-specific antibodies
Hepatitis B-specific antibodies
circulating HIV particles
HIV-specific DNA
Question 5 10 pts
What is the cell surface receptor for HIV?
CD4
CD8
MHCII
HIV
Question 6 10 pts
What is the likely origin of HIV-1?
infection of humans by a simian virus native to the chimpanzee
germ warfare research by the CIA
sexually transmitted to humans through relations with sheep
a new human-chimpanzee hybrid virus accidentally made in a laboratory with recombinant DNA
Question 7 10 pts
How does AZT block the production of infectious virus?
It acts as a substitute for a DNA nucleotide that can only be inserted by the viral reverse transcriptase. The presence of the AZT in the DNA aborts the production of new viral DNA.
It directly blocks the reverse transcriptase.
It blocks the protease that cuts apart the three viral proteins, which is a necessary step during viral synthesis.
It blocks the adsorption of the virus to the CXCR4 and CCR5 receptors on the T-cell surface.
Question 8 10 pts
How do protease inhibitors work?
It blocks the protease that cuts apart the three viral proteins, which is a necessary step during viral synthesis.
It directly blocks the reverse transcriptase.
It acts as a substitute for a DNA nucleotide that can only be inserted by the viral reverse transcriptase. The presence of the AZT in the DNA aborts the production of new viral DNA.
It blocks the adsorption of the virus to the CXCR4 and CCR5 receptors on the T-cell surface.
Question 9 10 pts
What are the 2 most common causes of a false negative result in the HIV test?
1.
2.
Questions 10-13
The next set of 4 questions deal with the possible ways that a virus, not necessarily the HIV, can enter the body. Answer TRUE or FALSE to each question.
Question 10 2.5 pts
Some viruses can enter the body through breaks in the skin.
True
False
Question 11 2.5 pts
Some viruses can enter the body through the anal/genital tract.
True
False
Question 12 2.5 pts
Some viruses can enter the body through the oral cavity and the digestive tract.
True
False
Question 13 2.5 pts
Some viruses can enter the body through inhalation via the respiratory tract.
True
False
