HIST 3D Lecture Notes - Lecture 9: Cholera, Motility, Immunology
Document Summary
Harvest of the lab: t. b. and postulates, 1882. The information transferred to everywhere before the paper came out. We came to a stage where the protocol and technique used were becoming very important. The koch"s postulates: find the bacterial agent in all cases, isolate and culture, inoculate the bacteria into an experimental animal, re-isolate the agent. The postulates the touchdown for bacteriology: koch and cholera, 1883-84. Another opportunity for koch, the cholera broke out in egypt. French team got there rst, organized by pasteur: concerned with microscopic identi cation of the pathogen, animal inoculation experiment, main action of cholera was taking place in the blood. Koch expedition: brought along a complete lab set, alexandria: focus on the intestinal symptoms. Culture the organism in an alkaline environment. Inoculated the dog bypass the stomach: carried on to india. Brought it back: loe er and diphtheria. Diphtheria: grow in the throat, membrane block the windpipe. Discovery of the micro bacteria: berlin as center.
