NURS 3220 Lecture Notes - Lecture 3: Hyaluronic Acid, Thalamus, Tramadol

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Chronic pain disorders: osteoarthritis, rheumatoid arthritis, and fibromyalgia. Why these 3: to compare inflammatory vs. (cid:498)non-inflammatory(cid:499) arthritis, these disorders affect many people, causing pain and disability you will see them frequently, good examples of chronic pain treatment. Systemic autoimmune rheumatic diseases: diffuse inflammatory vascular lesions, degeneration of connective tissue. Ra is a pathology of the synovial membrane: rheumatoid synovitis, growth of new blood vessels (cid:498)pannus(cid:499) that extend from synovium to articular cartilage. Inflammatory cells in pannus destroy adjacent cartilage and bone (irreversible) Joint inflammation: symmetric, polyarticular (several joints, reduced joint motion, ankylosis (fusion) Joint deformities, joints feel spongy: stiffness after rest, lasting more than 1 hr, muscle loss, systemic: fatigue, anorexia, weight loss. Joint deformities in ra (and joints in ra bouchard"s nodules: swan"s neck, ulnar drift, nodes, muscle wasting, so joints are pulled toward the stronger side, hip and leg deformities.

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