BIPN 105 Lecture Notes - Lecture 9: Oncotic Pressure, Extracellular Fluid, Starling Equation
1 Apr 2019
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Artery -> arterioles -> capillary bed -> venules -> veins: arterioles: resistance vessels. Relative to size, has most smooth muscle, so can vasoconstrict and vasodilate a lot: arteries and veins: do have smooth muscle, but constrict and dilate to a lesser extent, capillaries: don"t have smooth muscles. Transport across capillary walls: simple diffusion occurs if they are lipophilic: o2, co2. If charged or lipophobic, go through tight junctions: large molecules like proteins and hormones move through vesicle transport and fenestrations (big pores, found in bone or liver, filtration: water movement, which carry water-soluble molecules. Higher bp -> higher capillary pressure -> more fluid moves out of capillary. If is positive, water is leaving the capillary. If is negative, water is moving into the capillary. In the veins, is -2 mm hg and water enters: using the equation, in the arteries, is 13 mm hg, and water is leaving.
