BIOL 1301 Lecture 8: biol10031903-notes-biology-notes-from-lectures-and-hb-online
Document Summary
Nucleotides building blocks of dna: sugar (deoxyribose) + nitrogenous base (actg/acug) + phosphate group: bases: adenine, cytosine, thymine, guanine. *enzymes can only add nucleotides to 3" end of nucleotides (cid:198) a continuous strand (3" end opened up) and lagging strand (5" end opened up) Lagging strand: rna primer added to individual sections, dna helicase attaches nucleotides in opp. direction of unwinding, rna primer removed + sections (okazaki fragments) joined. Protein synthesis from dna: transcription: dna (cid:198) rna. Initiation: rna polymerase + sigma factor = holoenzyme binds to promoter region of. *open reading frames: sensible transcript w/ start codon and few hundred codons till stop codon. Rna ribonucleic acid: rna: (cid:131) single strand (cid:131) u bonds with t instead of a (cid:131) 2" h instead of 2" oh group. Interphase: non-dividing: g1: normal cell functions, checkpoint for division, synthesis (s): dna replicates (as above) 2 copies of each chromosome, g2: prepares for mitosis, checkpoint to check replication.