MCB 150 Lecture Notes - Lecture 6: Deoxycytidine Triphosphate, Purine, Adenine
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6 Dec 2017
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Nucleotides can exist with a single-phosphate group, two-phosphate groups or three- phosphate groups. 1 nucleoside + 1 phosphate group = nucleoside monophosphate. 1 nucleoside + 2 phosphate group = nucleoside diphosphate. All nts in dna chain have same 5-carbon sugar and a phosphate group. All nts in rna chain have same 5-carbon sugar and a phosphate group. For nucleotides of each of these nucleic acids, all that differs in the base. Pyrimidine bases are cytosine (c) and thymine (t) Monomer: deoxyribonucleotides (or deoxyribonucleoside triphosphates, or dntps) Pyrimidine bases are cytosine (c) and uracil (u) Purine bases are adenine (a) and guanine (g) Take one of the phosphate groups from the pyrophosphate group ppi 2 linked. 3" oh group + a h atom are lost as water incoming nucleotide create a new covalent bond between it and the 3" hydroxyl group.
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