BIOLOGY 152 Lecture Notes - Lecture 1: Phenotypic Trait, Escherichia Coli, Petri Dish

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Premise: e coli put into petri dish with increasing amounts of antibiotic. As time progressed, mutations caused bacteria to be immune to antibiotic. Random mutation altered the function of an existing enzyme. E coli developed mutations continuously until it was immune to antibiotic. 30 times stronger than it used to be. Used e coli because small and simple. Despite being small and simple they are modern and evolved. Only some developed resistance due to randomness of mutations. If performed with some bacteria that already had resistance and some that did not, pre-existing resistant bacteria would dominate. growth refers to overall population of the culture. When it causes advantageous genotype it can be selected for. Are not moving towards something- no goal. Does not occur quickly or in one step. Refers to random changes that underlie revolution. Term is from book by mlodinow on the randomness of these mutations. Ancient idea that humans were the pinnacle of evolutionary development.

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